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During copulation the cloaca or vagina gets inseminated , and then the spermatozoa move through chemotaxis to the ovum inside a Fallopian tube or the uterus.

Sperm activation has been shown to be caused by calcium ionophores in vitro , progesterone released by nearby cumulus cells and binding to ZP3 of the zona pellucida.

The cumulus cells are embedded in a gel-like substance made primarily of hyaluronic acid, and developed in the ovary with the egg and support it as it grows.

The initial change is called "hyperactivation", which causes a change in spermatozoa motility. They swim faster and their tail movements become more forceful and erratic.

A recent discovery links hyperactivation to a sudden influx of calcium ion into the tails. The whip-like tail flagellum of the sperm is studded with ion channels formed by proteins called CatSper.

These channels are selective, allowing only calcium ions to pass. The opening of CatSper channels is responsible for the influx of calcium. The sudden rise in calcium levels causes the flagellum to form deeper bends, propelling the sperm more forcefully through the viscous environment.

Sperm hyperactivity is necessary for breaking through two physical barriers that protect the egg from fertilization.

The second process in sperm activation is the acrosome reaction. This involves releasing the contents of the acrosome, which disperse, and the exposure of enzymes attached to the inner acrosomal membrane of the sperm.

This occurs after the sperm first meets the egg. This lock-and-key type mechanism is species-specific and prevents the sperm and egg of different species from fusing.

There is some evidence that this binding is what triggers the acrosome to release the enzymes that allow the sperm to fuse with the egg. ZP3, one of the proteins that make up the zona pellucida, then binds to a partner molecule on the sperm.

Enzymes on the inner acrosomal membrane digest the zona pellucida. After the sperm penetrates the zona pellucida, part of the sperm's cell membrane then fuses with the egg cell's membrane, and the contents of the head diffuse into the egg.

Upon penetration, the oocyte is said to have become activated. It undergoes its secondary meiotic division, and the two haploid nuclei paternal and maternal fuse to form a zygote.

In order to prevent polyspermy and minimise the possibility of producing a triploid zygote, several changes to the egg's zona pellucida renders them impenetrable shortly after the first sperm enters the egg.

Spermatozoa can be stored in diluents such as the Illini Variable Temperature IVT diluent, which have been reported to be able to preserve high fertility of spermatozoa for over seven days.

Semen cryopreservation can be used for far longer storage durations. For human spermatozoa, the longest reported successful storage with this method is 21 years.

From Wikipedia, the free encyclopedia. Motile sperm cell. A sperm cell attempts to penetrate an ovum coat to fertilize it. Play media.

Dimensions of the human sperm head measured from a 39 year-old healthy subject. See also: Sperm and Female sperm storage. Main article: Spermatogenesis.

Main article: Acrosome reaction. CBC News. Retrieved Journal of Fluid Mechanics. Bibcode : JFM Retrieved 20 May Gamete Research. Sperm guidance in mammals Nature Reviews: molecular cell biology.

Biology of Reproduction. Human Reproduction Update. Advances in Experimental Medicine and Biology. Molecular Human Reproduction.

Molecular Reproduction and Development. Fertility and Sterility. Environmental Health Perspectives. Toxicological Sciences.

Analogy to apoptosis of somatic cells". Exp Cell Res. Bibcode : Sci BBC News. Bibcode : Natur. Bibcode : PNAS Demerec, M. Biology of Drosophila.

New York: Wiley. DNA Repair. Bibcode : PNAS.. Scientific Reports. Bibcode : NatSR Current Therapy in Medicine of Australian Mammals.

Csiro Publishing. Journal of Clinical Endocrinology and Metabolism. Reproduction, Fertility and Development. Sex portal. Male reproductive system.

Seminal vesicles excretory duct Prostate Urethral crest Seminal colliculus Ejaculatory duct sinus ducts utricle evolution in monotremes Bulbourethral glands.

You're so far away from reality that it would take pages and pages to set you straight. How about you go look up the difference between "atoms", "molecules", and "cells", and we can go from there.

Can't give you a specific number, many billions though. And they aren't made from just one type of atom, they are made from different molecules atoms bonded together.

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